Experimental Pharmacology

This book is the thoroughly revised, enlarged and updated edition of the unique book designed for medical and pharmacy students which focuses on the practical and experimental aspects of pharmacology. Intended to help the students to bridge the gap between theoretical knowledge and practical application, it will be particularly useful for MBBS, MD (pharmacology), DNB (pharmacology), BPharm, MPharm, MSc (medical pharmacology) students, and research scholars. Key Features of the book Ø Focuses on practical application. Ø Explains how to conduct experiments and interpret the results. Ø Clear and visual contents enriched with numerous charts, flow diagrams, and graphs Ø that simplify complex pharmacological concepts. Ø Profusely provides viva voce questions in experimental pharmacology. Ø Comprehensive covers the essential topics: v Details of laboratory animals, anaesthesia and euthanasia in experimental animals, blood withdrawal in laboratory animals, and routes of drug administration. v CCSEA, IAEC and alternatives to animal experiments. v Pharmacology of receptors and autonomic nervous system. v Efficacy, potency, potentiation, antagonism, and bioassay. v Experiments based on (a) spasmogenics and spasmolytics on smooth muscles; (b) miotics, mydriatics, and local anaesthetics; (c) cardiac stimulants and cardiac depressants; and (d) vasopressors and vasodepressors on BP. v Screening methods: How to test new drugs for potential CNS stimulant and depressant activity, analgesic, local anaesthetic, antiepileptic, anti-inflammatory and antipsychotic activity. Highlights of the Second Edition v New chapters including: a) Anaesthesia and euthanasia in experimental animals b) Alternatives to animal experiments c) CCSEA and IAEC d) Withdrawal of blood in experimental animals e) Detailed explanation of DRC, pD2, pA2, Schild plot, and Bioassay methods f) Drug screening methods: Antianxiety, antiepileptic, antipsychotic, motor coordination and anti-inflammatory activity g) A large number of Viva voce questions, short and long answer questions h) A large number of graphs, and flow charts